Asclera® involves an injection through a needle into the vein. You may experience mild discomfort during the injections. Each Asclera® treatment lasts 30 to 60 minutes and most patients require several treatments to achieve maximum results. Side effects are minimal and can include itchiness and redness near the injection site. After treatment, you will need to compress the treated area for several days, but can return to normal activities almost immediately. You should avoid strenuous exercise, sun exposure, hot tubs, or plane flights for several days after treatment.